Status:

UNKNOWN

Effect of Fatty Liver Disease on Bone Density

Lead Sponsor:

Sohag University

Conditions:

Non-Alcoholic Fatty Liver Disease

Osteoporosis

Eligibility:

All Genders

20-60 years

Brief Summary

Non Alcohlic Fatty Liver (NAFLD) is a spectrum of diseases that ranges from accumulation of fat in the liver (Hepatosteatosis) that may be accompanied by inflammation (Steatohepatitis) to necrosis, fi...

Detailed Description

All included patients will be subjected to the following: 1. Complete history taking including age, sex, current medical history (e.g. hypertension, diabetes mellitus, cardiovascular disease, renal, ...

Eligibility Criteria

Inclusion

  • Males (20-60 years old ) and premenopausal females with NAFLD diagnosed by Fibroscan

Exclusion

  • (i) Patients aged \<20 years or \>60years. (ii) Alcohol consumption of ≥30 g/day in men or≥20 g/day in women. (iii) Subjects with suspected or proven any other liver disease other than NAFLD as (viral hepatitis, drug-induced liver injury, autoimmune liver disease, Wilson's disease or primary biliary cholangitis).
  • (iv) Postmenopausal females to avoid the increased risk of osteoporosis in those patients due to hormonal changes.
  • (v) Patients with conditions known to affect bone metabolism, such as kidney, thyroid or parathyroid diseases.

Key Trial Info

Start Date :

May 1 2021

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

May 1 2022

Estimated Enrollment :

80 Patients enrolled

Trial Details

Trial ID

NCT04850547

Start Date

May 1 2021

End Date

May 1 2022

Last Update

April 20 2021

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