Status:
COMPLETED
Efficacy of Dexamethasone or Adrenaline in Inferior Alveolar Nerve Block
Lead Sponsor:
Tribhuvan University, Nepal
Collaborating Sponsors:
National Medical College, Birgunj, Nepal
Conditions:
Oral Surgical Procedure
Eligibility:
All Genders
18-60 years
Phase:
PHASE3
Brief Summary
Oral and dental professionals were responsible for the discovery of anaesthesia, given their close day-to-day contact with pain and, hence, their motivation to seek the means to alleviate it. Currentl...
Detailed Description
Background : Oral and dental professionals were responsible for the discovery of anaesthesia, given their close day-to-day contact with pain and, hence, their motivation to seek the means to alleviat...
Eligibility Criteria
Inclusion
- patients above age 18 who need oral surgery under local anaesthesia and could understand and willing to take part in the study were selected.
- contraindications to Dexamethasone (i.e., peptic ulcer, renal insufficiency, pregnant women or lactating females ),
- allergy to NSAIDs ie piroxicam
- ASA physical status \> III
- any type of surgery other than a mention surgery performed under general anaesthesia
- -patients with any condition precluding the limitation of intra-operative trial drugs ( lignocaine, adrenaline) administration (i.e., significant coronary artery disease, congestive heart failure)
- those receiving any premedications (including opioids, benzodiazepines, and clonidine )
- antibiotics or anti-inflammatory drugs within two weeks of the study entry. Also, radiograph showing high and bifid mandibular foramen were non included.
Exclusion
- Subject who had to consume analgesic drugs other than the piroxicam 20 mg
- The subjects who did not respond on the VAS scale for 24 hourly and did not come for follow-up for 2nd and 7th postoperatively.
Key Trial Info
Start Date :
August 1 2020
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
February 28 2021
Estimated Enrollment :
83 Patients enrolled
Trial Details
Trial ID
NCT04850885
Start Date
August 1 2020
End Date
February 28 2021
Last Update
April 22 2021
Active Locations (1)
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1
Saroj Prasad Deo
Birgunj, Two, Nepal, 43000