Status:
COMPLETED
Is the Lack of Prior Exposure to Sperm Antigens Associated With Worse Neonatal and Maternal Outcomes?
Lead Sponsor:
Istituto Clinico Humanitas
Conditions:
Obstructive Azoospermia
Obstetric Complication
Eligibility:
All Genders
18-43 years
Brief Summary
The objective of this study is to determine if the lack of exposure to sperm antigens is associated with worse maternal and neonatal outcomes in pregnancies obtained after ICSI (intracytoplasmic sperm...
Detailed Description
Several studies investigated the role of paternal factors in the development of preeclampsia; in particular, they analyzed the correlation between the vaginal exposure to male partner's semen and the ...
Eligibility Criteria
Inclusion
- Inclusion Criteria for case arm:
- primary infertility
- diagnosis of obstructive azoospermia
- ICSI-TESE cycles
- Inclusion Criteria for control arm:
- primary infertility
- ICSI cycles with sperm from ejaculate
- Exclusion Criteria:
- pre-gestational hypertension
- pre-gestational diabetes
Exclusion
Key Trial Info
Start Date :
January 1 2010
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
December 31 2019
Estimated Enrollment :
400 Patients enrolled
Trial Details
Trial ID
NCT04852237
Start Date
January 1 2010
End Date
December 31 2019
Last Update
April 22 2021
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