Status:

COMPLETED

Comparative Effectiveness of Biologics or Small Molecule Therapies in Inflammatory Bowel Disease (IBD)

Lead Sponsor:

University of North Carolina, Chapel Hill

Collaborating Sponsors:

Patient-Centered Outcomes Research Institute

Crohn's and Colitis Foundation

Conditions:

Crohn's Disease

Ulcerative Colitis

Eligibility:

All Genders

18+ years

Brief Summary

The purpose of this study is to assess effectiveness of vedolizumab versus ustekinumab in patients with Crohn's disease and vedolizumab versus tofacitinib in patients with ulcerative colitis, after no...

Detailed Description

This study is a secondary analysis using data from participants in the IBD Partners and SPARC-IBD cohorts. Data received from IBD Partners consists of patient-reported outcomes gathered via online sur...

Eligibility Criteria

Inclusion

  • age greater than or equal to 18;
  • diagnosis of CD or UC (as reported by participant for IBD Partners registry and/or physician for SPARC-IBD cohort);
  • initiated vedolizumab or ustekinumab for CD, or initiated vedolizumab or tofacitinib for UC; treated with anti-TNF prior to vedolizumab/ustekinumab/tofacitinib.

Exclusion

  • less than 18 years of age

Key Trial Info

Start Date :

July 25 2019

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

December 15 2022

Estimated Enrollment :

465 Patients enrolled

Trial Details

Trial ID

NCT04852666

Start Date

July 25 2019

End Date

December 15 2022

Last Update

June 14 2024

Active Locations (2)

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Page 1 of 1 (2 locations)

1

Crohn's & Colitis Foundation

New York, New York, United States, 10017

2

University of North Carolina

Chapel Hill, North Carolina, United States, 27599-7555

Comparative Effectiveness of Biologics or Small Molecule Therapies in Inflammatory Bowel Disease (IBD) | DecenTrialz