Status:
RECRUITING
Impact Study of Cholera Vaccination in Endemic Areas - Clinical Surveillance
Lead Sponsor:
Epicentre
Collaborating Sponsors:
Wellcome Trust
Médecins Sans Frontières, France
Conditions:
Cholera
Eligibility:
All Genders
Brief Summary
This project aims to fill this essential knowledge gap by assessing the impact of oral cholera vaccine mass campaigns in 2 sites (urban and rural) in DRC, described in this protocol. The evidence gene...
Detailed Description
The project will comprise three different components: 1. Clinical cholera surveillance to measure cholera diseases incidence in selected African hotspots targeted by vaccination. 2. Serial serologica...
Eligibility Criteria
Inclusion
- For Surveillance in study CTCs
- All patients presenting at the time of the study to any selected Cholera Treatment Center/Cholera Treatment Unit (CTC/CTU), matching the case definition and giving his/her consent (or assent for children 8 to 17 years old) to participate in the study will be eligible.
Exclusion
- Patients who decline to participate will be excluded from the study.
- Follow up of individuals with active cholera shedding:
- Inclusion Criteria:
- present to any selected CTC/CTU, match the case definition, participate to the clinical surveillance activity and test positive to RDT OR
- Be a household member of a person respecting inclusion criteria 1. AND for whom the head of the household has provided verbal consent to participate AND giving his/her consent (or assent for children 8 to 17 years old) to participate in the study will be eligible.
Key Trial Info
Start Date :
May 11 2021
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 31 2026
Estimated Enrollment :
6000 Patients enrolled
Trial Details
Trial ID
NCT04853186
Start Date
May 11 2021
End Date
December 31 2026
Last Update
September 19 2024
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Anais Broban
Goma, Democratic Republic of the Congo