Status:
UNKNOWN
Deep Brain Stimulation Therapy and Intestinal Microbiota
Lead Sponsor:
The First Affiliated Hospital with Nanjing Medical University
Conditions:
Deep Brain Stimulation
Gastrointestinal Microbiome
Eligibility:
All Genders
18-80 years
Brief Summary
This study aims to observe the changes of intestinal microbiota after deep brain stimulation (DBS) therapy for Parkinson's disease, and explore the role of intestinal microbiota in the neuroprotective...
Eligibility Criteria
Inclusion
- \> 18 years of age;
- Primary Parkinson's disease diagnosed according to British Brain Bank criteria (Hoehn and Yahr);
- Deep brain stimulator therapy;
- Sign the informed consent.
Exclusion
- Use of probiotics or probiotics during the study;
- Use antibiotics against intestinal bacteria at present or within the last 1 month;
- With cognitive dysfunction or mental illness;
- With severe diseases or is not expected to survive for more than a year;
- A history of gastrointestinal surgery;
- AIDS patients, hepatitis B/C positive.
Key Trial Info
Start Date :
April 15 2021
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 31 2022
Estimated Enrollment :
30 Patients enrolled
Trial Details
Trial ID
NCT04855344
Start Date
April 15 2021
End Date
December 31 2022
Last Update
April 22 2021
Active Locations (1)
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1
the Hospital Research Ethics Committee of the First Affiliated Hospital of Nanjing Medical University
Nanjing, Jiangsu, China, 210029