Status:
NOT_YET_RECRUITING
THC + CBD and Memory Study
Lead Sponsor:
Hartford Hospital
Collaborating Sponsors:
Yale University
Conditions:
Marijuana Use
Cannabis Use
Eligibility:
All Genders
18-40 years
Phase:
EARLY_PHASE1
Brief Summary
Memory deficits are one of the most consistently observed cognitive effects of marijuana use. There is evidence that some decrements attributable to the primary psychoactive ingredient, delta-9-tetrah...
Detailed Description
With increased legalization and medicalization of marijuana (MJ), there is an urgent need to understand the acute effects of use. One of the most consistently observed cognitive outcomes associated wi...
Eligibility Criteria
Inclusion
- Right-handed
- Prior MJ users (has used MJ at least once in the past year, but no more than 1x/month in the past 12 months)
- Medically healthy (as determined by medical history and treatment)
- Adequate comprehension of English in order to complete study materials
- Acceptable birth control method for women (i.e., no copper IUD or any device that is not MRI safe)
Exclusion
- Participant currently uses psychoactive medications or substances
- Psychiatric diagnoses (determined by DSM-V)
- Participant heavily or regularly uses MJ (more than 1x/month in the past year)
- Current or past substance dependence (including MJ)
- Positive urine toxicology screens
- Positive pregnancy screens
- MRI contraindications (e.g., heart pacemaker)
Key Trial Info
Start Date :
December 1 2025
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 30 2026
Estimated Enrollment :
9 Patients enrolled
Trial Details
Trial ID
NCT04855526
Start Date
December 1 2025
End Date
December 30 2026
Last Update
March 17 2025
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