Status:

RECRUITING

Dose-staged Gamma Knife Radiosurgery Versus Microsurgical Resection

Lead Sponsor:

Medical University of Vienna

Conditions:

Brain Metastases

Eligibility:

All Genders

18-90 years

Phase:

NA

Brief Summary

Background. Brain metastases (BM) are the most common intracranial tumor and occur in 20-40% of all oncological patients. The most common primary cancer in brain metastases is lung cancer, followed by...

Eligibility Criteria

Inclusion

  • Patients over 18 years and under 90 years
  • Patients with KPS ≥70
  • Patients with NSCLC, melanoma, breast cancer or renal cancer as primary tumor
  • Maximum of three brain metastases on the diagnostic MRI
  • Tumor volume of 8-20 ccm3 on the diagnostic MRI
  • Lobular brain metastases
  • Patients without any contraindications for both treatment options
  • Written, signed informed consent for study particaption after study explanation

Exclusion

  • Patients under 18 years and over 90 years
  • Patients with KPS \<70
  • Patients with other primary tumor
  • More than three brain metastases on the diagnostic MRI
  • Tumor volume \<8 or \>20 ccm3 on the diagnostic MRI
  • Patients with contraindications for both treatment options

Key Trial Info

Start Date :

July 1 2020

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

December 1 2025

Estimated Enrollment :

100 Patients enrolled

Trial Details

Trial ID

NCT04857905

Start Date

July 1 2020

End Date

December 1 2025

Last Update

January 5 2024

Active Locations (1)

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Department of Neurosurgery, Medical University of Vienna

Vienna, Austria, 1090

Dose-staged Gamma Knife Radiosurgery Versus Microsurgical Resection | DecenTrialz