Status:
COMPLETED
Chronic Passive Heating in Individuals With T2DM
Lead Sponsor:
University of Portsmouth
Collaborating Sponsors:
Portsmouth Hospitals NHS Trust
Conditions:
Type2 Diabetes
Eligibility:
All Genders
35+ years
Phase:
NA
Brief Summary
Type 2 diabetes mellitus (T2DM) is a metabolic condition characterized by chronic hyperglycemia and progressive insulin resistance, which progressively lead to macro- and microvascular damage and subs...
Detailed Description
Current estimates suggest 422 million people worldwide live with a form of diabetes, of which \~ 90% have type 2 diabetes mellitus (T2DM). The total direct and indirect cost of care for individuals wi...
Eligibility Criteria
Inclusion
- Male or female (post-menopausal) aged 35 years or above.
- Diagnosed with T2DM as defined by the WHO (≥48 mmol/mol).
- Participant is willing and able to give informed consent for participation in the study.
- Participant is able to understand and fully cooperate with the study protocol.
Exclusion
- Severe peripheral neuropathy (to the point to which they cannot sense temperature)
- Uncontrolled hypertension (≥180 systolic / 100 diastolic mmHg)
- Taking any medication which may interfere with data interpretation or safety
- Who have had a myocardial infarction or cerebro-vascular event
- Any cardiac abnormalities which restrict hard exercise
- Current smokers or who have stopped within 3 months
- Participant is unable to understand and/or fully cooperate with the study protocol
- Any other serious medical condition which would interfere with data interpretation or safety will be excluded from participation.
- Skin ulcerations
- Eczema
- Pre-existing postural hypertension
- Existing cardiac diseases (identified during screening)
Key Trial Info
Start Date :
May 24 2021
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 19 2022
Estimated Enrollment :
17 Patients enrolled
Trial Details
Trial ID
NCT04858321
Start Date
May 24 2021
End Date
December 19 2022
Last Update
January 3 2025
Active Locations (1)
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1
Department of Sport and Exercise Science
Portsmouth, Hampshire, United Kingdom, PO1 2ER