Status:
COMPLETED
Geriatric Anorexia Study
Lead Sponsor:
Boston University
Conditions:
Healthy
Eligibility:
All Genders
65-85 years
Brief Summary
Reduction in appetite and/or food intake among older individuals is referred to as anorexia of aging (AOA, also known as Geriatric Anorexia). AOA is linked with myriad comorbidities associated with ag...
Detailed Description
This is a study to evaluate movement, metabolism, body weight composition, glucose levels, and nutritional scale in healthy adults. Subjects, age 65 to 85 years will be recruited. The proposed study ...
Eligibility Criteria
Inclusion
- \[separated into the three groups based on the Fried Criteria: 0, 1-2, 3 or above\]
- Male or female participants aged 65 - 85 years.
- No clinically significant health problems other than well controlled chronic conditions (e.g., allergies and dermatitis)
- No recent hospitalizations/acute events in last 12 months.
- No active or recent (within 12 months) cancer diagnosis except skin cancer (limited to only non-complicated Squamous Cell Carcinoma (SCC)/Basal Cell Carcinoma (BCC)).
- Body mass index (BMI) \< 30 kg/m2
- Able to understand and cooperate with study procedures and able to read, understand and provide informed consent. Evidence of a personally signed and dated informed consent document indicating that the participant has been informed of all pertinent aspects of the study
- Participants should not have any food aversion which could influence their food selection if standardized meals are used as part of the protocol.
- Native English speakers or demonstrated fluency in English as determined by the Investigator.
- Wide Range Achievement Test (WRAT-4) Word Reading Subtest equivalent to 8th grade reading level or greater.
- Normal or corrected-to-normal vision
Exclusion
- Treatment with an investigational drug within 30 days of enrollment
- A moderate to severe alcohol use disorder diagnosis within 6 months of the screening as disclosed by the subject
- Subjects who are investigational site staff members directly involved in the conduct of the study and their family members, site staff members otherwise supervised by the investigator, or subjects who are Boston University/Boston Medical Center directly involved in the conduct of the study
- Inability to comply with study requirements.
- Has any clinically significant medical disorder, condition, disease or clinically significant finding at screening that precludes subject's participation in study activities including any self-reported diagnosis of eating disorders.
- Participants with electronic implant devices, such as pacemaker.
- Non-English Reader as measured by the WRAT-4.
Key Trial Info
Start Date :
April 27 2021
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
December 15 2021
Estimated Enrollment :
51 Patients enrolled
Trial Details
Trial ID
NCT04858932
Start Date
April 27 2021
End Date
December 15 2021
Last Update
February 1 2022
Active Locations (1)
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1
Evans Biomedical Research Center
Boston, Massachusetts, United States, 02118