Status:

COMPLETED

Normal Range of TSH and FT4 in Pregnancy

Lead Sponsor:

Sehit Prof. Dr. Ilhan Varank Sancaktepe Training and Research Hospital

Conditions:

Hypothyroidism

Pregnancy Related

Eligibility:

FEMALE

18-50 years

Brief Summary

Physiological changes necessitate the use of pregnancy-specific reference ranges for thyrotrophin (TSH) and free T4 (FT4) to diagnose thyroid dysfunction during pregnancy. Although many centers use fi...

Detailed Description

Serum thyroid function tests (including T3, T4, TSH, Anti-TPO) will be obtained from the singleton pregnancies in the first, second, and third trimester to determine the local specific normal ranges.

Eligibility Criteria

Inclusion

  • Singleton pregnancy
  • Free of pre-existing thyroid disease
  • That do not use thyroid interfering medication
  • That did not undergo IVF treatment
  • TPOAb negative

Exclusion

  • Adolescent pregnancy
  • Patient with pre-existing thyroid disease
  • TPOAb positive
  • Patient using thyroid interfering medication
  • That had IVF treatment

Key Trial Info

Start Date :

April 1 2021

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

September 1 2021

Estimated Enrollment :

528 Patients enrolled

Trial Details

Trial ID

NCT04860622

Start Date

April 1 2021

End Date

September 1 2021

Last Update

September 29 2021

Active Locations (1)

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Sehit Prof Dr Ilhan Varank Sancaktepe Training and Research Hospital

Istanbul, Turkey (Türkiye)