Status:
UNKNOWN
Combination of Duloxetine and Pregabalin to Improve Postoperative Pain
Lead Sponsor:
Cairo University
Conditions:
Postoperative Pain
Eligibility:
All Genders
18-40 years
Phase:
PHASE1
Brief Summary
Postoperative pain is mediated by different mechanisms at multiple neural sites. Thus, multimodal analgesics can reduce the postoperative pain. Although Opioids are considered the analgesics of choice...
Eligibility Criteria
Inclusion
- Inclusion criteria:
- Patients aged from 18 to40 years.
- ASA I-II.
- undergoing elective mega -liposuction surgery
- BMI from 18 to 50 kg/m2
- 2\. Exclusion criteria:
- Patient refusal
- Contraindication or chronic use (consistent use for longer than 3 months) to any of the study drugs ASA III-IV.
- Patients aged less than 18 or more than 40.
- Body mass index \>50.
- Suffered from severe psychiatric disease or drug addiction;
- Chronic opioid consumption,
- a history of regular sedatives or anticonvulsants intake, serious organ disease or dysfunction
- inability to use a PCA device
- History of parenteral or oral analgesic intake within the last 48hours.
Exclusion
Key Trial Info
Start Date :
May 15 2021
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
June 15 2023
Estimated Enrollment :
72 Patients enrolled
Trial Details
Trial ID
NCT04862845
Start Date
May 15 2021
End Date
June 15 2023
Last Update
April 28 2021
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