Status:
UNKNOWN
Brain Activity During Gait in Parkinson's
Lead Sponsor:
Northumbria University
Collaborating Sponsors:
Parkinson's Foundation
Northumbria Healthcare NHS Foundation Trust
Conditions:
Parkinson Disease
Eligibility:
All Genders
50+ years
Brief Summary
Lay Summary: Walking problems, such as slow and short steps, are very common in Parkinson's disease and lead to increased falls risk, as well as reduced mobility and quality of life. Walking issues a...
Eligibility Criteria
Inclusion
- Clinical diagnosis of Parkinson's by a movement disorder specialist according to United Kingdom (UK) brain bank criteria
- Hoehn \& Yahr (H\&Y) stage I-III
- Aged \>50 years
- Able to walk and stand unaided
- Adequate hearing (as evaluated by the whisper test; stand 2m behind subject and whisper a 2 syllable word, subject repeats word) and vision capabilities (as measured using a Snellen chart - 6/18-6/12).
- Stable medication for the past 1 month and anticipated over a period of 6 months
Exclusion
- Psychiatric co-morbidity (e.g., major depressive disorder as determined by Geriatric Depression Scale - short form (GDS-15); \<10 \[26\])
- Clinical diagnosis of dementia or other severe cognitive impairment (Montreal cognitive assessment \<21 \[27\])
- History of stroke, traumatic brain injury or other neurological disorders (other than PD, for the PD group)
- Acute lower back or lower extremity pain, peripheral neuropathy, rheumatic and orthopaedic diseases
- Unstable medical condition including cardio-vascular instability in the past 6 months
- Unable to comply with the testing protocol or currently participating in another interfering research project
- Interfering therapy
Key Trial Info
Start Date :
October 1 2020
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
November 30 2022
Estimated Enrollment :
80 Patients enrolled
Trial Details
Trial ID
NCT04863560
Start Date
October 1 2020
End Date
November 30 2022
Last Update
April 28 2021
Active Locations (3)
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1
Oregon Health & Science University
Portland, Oregon, United States, 97239
2
Northumbria University
Newcastle upon Tyne, United Kingdom, NE7 7XA
3
Northumbria Healthcar NHS foundation trust
North Shields, United Kingdom, NE29 8NH