Status:
RECRUITING
ECOCAPTURE for the Assessment of Apathy Under Real-life Conditions
Lead Sponsor:
Institut National de la Santé Et de la Recherche Médicale, France
Conditions:
Frontotemporal Dementia, Behavioral Variant
Alzheimer Disease
Eligibility:
All Genders
40-85 years
Brief Summary
ECOCAPTURE@HOME is a study which is currently being developed with the objective to capture the behavioral signature of apathy in everyday life context through remote monitoring of participants' behav...
Detailed Description
Apathy, a common neuropsychiatric symptom associated with dementia, has a strong impact on both patients' and caregivers' quality of life. In spite of its debilitating consequences, apathy is still po...
Eligibility Criteria
Inclusion
- Inclusion Criteria for patients:
- Diagnosis of bvFTD according to Rascovsky's international criteria for the bvFTD group / diagnosis of AD according to Dubois's international criteria for the AD group;
- No evidence of any other cerebral pathology;
- A Mini-Mental State Evaluation (MMSE) score superior or equal to 10 (to minimise the effect of confounding factors related to very severe cognitive impairment);
- Aged between 40 and 85;
- No evidence of any psychiatric condition and a Montgomery-Åsberg Depression Rating Scale (MADRS) score inferior to 20 (to avoid confusion between depression and apathy);
- No evidence of excessive consumption of psychotropic drugs - for instance benzodiazepines, sleeping pills, etc. (due to their tranquilising effect);
- No major physical disability disrupting mobility;
- No heart pacemaker (which would compromise heart rate measuring).
- Inclusion Criteria for caregivers and partners of healthy control dyads:
- Aged between 40 and 85;
- No evidence of any psychiatric condition;
- A MADRS score inferior to 20;
- No evidence of excessive consumption of psychotropic drugs;
- No major physical disability disrupting mobility;
- No heart pacemaker.
- Exclusion Criteria:
- Persons in detention by judicial or administrative decision
- Person who is subject to a legal protection order
- Person submitted to an exclusion period due to the participation to another research
Exclusion
Key Trial Info
Start Date :
May 20 2022
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
May 1 2025
Estimated Enrollment :
120 Patients enrolled
Trial Details
Trial ID
NCT04865172
Start Date
May 20 2022
End Date
May 1 2025
Last Update
November 21 2024
Active Locations (1)
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1
ICM, Hôpital Salpêtrière
Paris, France, 75013