Status:

UNKNOWN

A Study to Evaluate the Tolerability, Safety, Pharmacokinetics of HEC89736 in Patients With Relapsed or Refractory B-cell Hematologic Malignancies

Lead Sponsor:

Sunshine Lake Pharma Co., Ltd.

Conditions:

Relapsed or Refractory B-cell Hematologic Malignancies

Eligibility:

All Genders

18+ years

Phase:

PHASE1

Brief Summary

Evaluate the safety, pharmacokinetics and efficacy of HEC89736 in patients with Relapsed or Refractory B-cell Hematologic Malignancies

Eligibility Criteria

Inclusion

  • Age is over 18 years old
  • Histologically or cytologically diagnosed patients with recurrent or refractory B-cell malignancies
  • ECOG performance status (PS) 0 \~ 1
  • Expected survival of \> or = 3 months

Exclusion

  • The use of PI3Ks as the target of anti-tumor drugs progress (due to intolerance group)
  • Received any other anti-cancer treatment within 4 weeks
  • Unable to swallow, chronic diarrhea and intestinal obstruction, there are many factors that affect drug use and absorption
  • Allergy, or known to have a history of allergy to the drug components

Key Trial Info

Start Date :

April 1 2021

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

April 1 2024

Estimated Enrollment :

80 Patients enrolled

Trial Details

Trial ID

NCT04865458

Start Date

April 1 2021

End Date

April 1 2024

Last Update

May 6 2022

Active Locations (2)

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Page 1 of 1 (2 locations)

1

Beijing Cancer Hospital

Beijing, Beijing Municipality, China

2

Jiangsu Province Hospital

Nanjing, Jiangsu, China