Status:
UNKNOWN
Radiation-induced Cardiac Toxicity After Non-small Cell Lung Cancer Radiotherapy
Lead Sponsor:
Military Institute od Medicine National Research Institute
Conditions:
Non-small Cell Lung Cancer
Radiation Toxicity
Eligibility:
All Genders
18+ years
Brief Summary
Despite the growing interest in investigating how the radiotherapy (RT) dose to anatomical substructures of the heart links to survival, the heart substructures at risk remain poorly defined. They are...
Detailed Description
BACKGROUND Radiation-induced cardiac toxicity after RT for breast cancer or haematological malignancies is well described, with various studies linking post-RT cardiac morbidity and mortality with rad...
Eligibility Criteria
Inclusion
- Age 18 or older
- Ability to provide informed consent
- Histologically confirmed non-small cell carcinoma of the lung
- Patient to receive standard RT with curative intent with or without concurrent or sequential CHT according to the institutional protocol
- ECOG performance status 0-1 within one month of accrual
- Negative pregnancy test within one month of accrual if woman is premenopausal
- Patient presented at multidisciplinary tumor board or quality-assurance rounds
- Satisfactory pulmonary function tests, i.e., forced expiratory volume during the first second (FEV1) ≥ 1.0 l (≥40%)
Exclusion
- Noncompliance with any of the inclusion criteria
- Pregnancy
- Prior RT to the thorax
- Patient to receive stereotactic body radiation therapy (SBRT)
Key Trial Info
Start Date :
May 1 2021
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
May 1 2024
Estimated Enrollment :
100 Patients enrolled
Trial Details
Trial ID
NCT04867564
Start Date
May 1 2021
End Date
May 1 2024
Last Update
July 23 2021
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Department of Radiotherapy, Military Institute of Medicine
Warsaw, Masovian Voivodeship, Poland, 04-141