Status:
RECRUITING
Magnetic Imaging for Diagnostic of Amyotrophic Lateral Sclerosis
Lead Sponsor:
University Hospital, Toulouse
Conditions:
Amyotrophic Lateral Sclerosis With Dementia
Eligibility:
All Genders
18-99 years
Phase:
NA
Brief Summary
Nearly 60% of Amyotrophic Lateral Sclerosis (ALS) patients have a low level of diagnostic certainty (possible, probable) at the time of diagnosis. In the absence of biomarkers, this diagnosis is based...
Detailed Description
The objective of this study is to show that the combination of ENMG and whole body muscle MRI (WB-MRI) can increase the diagnosis of definite ALS at the onset of the disease For 50 consecutive patient...
Eligibility Criteria
Inclusion
- Consent form signed by the patient
- Patients suspected ALS defined according Awaji Shima criteria (possible, probable, defined)
- Clinical assessment of upper motor neuron involvement
- Electrophysiologic assessment of lower motor neuron involvement
Exclusion
- inability to give informed consent
- a contraindication to MRI
- respiratory failure impairing ability to lie flat in the scanner.
- Patient placed under judicial protection or under another protective regime,
- Females who are pregnant
Key Trial Info
Start Date :
June 1 2021
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 1 2024
Estimated Enrollment :
50 Patients enrolled
Trial Details
Trial ID
NCT04868994
Start Date
June 1 2021
End Date
December 1 2024
Last Update
August 2 2024
Active Locations (1)
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1
Pascal CINTAS
Toulouse, France, 31000