Status:

RECRUITING

Treating Mild Traumatic Brain Injury With High Definition Transcranial Direct Current Stimulation

Lead Sponsor:

The University of Texas at Dallas

Conditions:

Traumatic Brain Injury

Eligibility:

All Genders

18-75 years

Phase:

NA

Brief Summary

The purpose of the study is to test whether low level electric stimulation, called transcranial Direct Current Stimulation (tDCS), on the part of the brain (i.e., presupplementary motor area) thought ...

Detailed Description

Using two treatment arms, the study will examine improvement of verbal retrieval and other cognitive deficits associated with remote traumatic brain injury by comparing (1) 1 milliamp transcranial dir...

Eligibility Criteria

Inclusion

  • Participants are to be between the ages of 18-75, have previously served in the US armed services, and have had a traumatic brain injury that has led to a verbal retrieval deficit based on neuropsychological testing criteria. Traumatic brain injury must be in the mild to moderate range based on evaluation, including, the Ohio State TBI Identification Method (administered by our research group). You must be fluent in speaking and reading English.

Exclusion

  • Exclusion criteria include a history of a psychological or neurological disorder, including, dementia of any type, epilepsy or other seizure disorders, severe traumatic brain injury, post-traumatic stress disorder, brain tumor, present drug abuse, stroke, blood vessel abnormalities in the brain, Parkinson's disease, Huntington's disease, or multiple sclerosis. Additionally, exclusion criteria include inability to give informed consent; cranial implants or skull defects that affect tDCS administration; and use of medications that interact with or potentially interact with tDCS effects, including, anti-convulsants, amphetamines, L-dopa, carbamazepine, sulpiride, pergolide, lorazepam, rivastigmine, dextromethorphan, D-cycloserine, flunarizine, ropinirole, or citalopram.

Key Trial Info

Start Date :

August 1 2021

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

September 30 2026

Estimated Enrollment :

136 Patients enrolled

Trial Details

Trial ID

NCT04869059

Start Date

August 1 2021

End Date

September 30 2026

Last Update

September 23 2025

Active Locations (1)

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Page 1 of 1 (1 locations)

1

The University of Texas at Dallas

Dallas, Texas, United States, 75235

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