Status:

COMPLETED

Advanced MRI Scan Before and After Radiation Therapy for the Detection of Intracranial Metastasis

Lead Sponsor:

M.D. Anderson Cancer Center

Collaborating Sponsors:

National Cancer Institute (NCI)

Conditions:

Malignant Solid Neoplasm

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

This clinical trial studies the different types of investigational imaging techniques called sequences during magnetic resonance imaging (MRI) of the head before and after radiation therapy in patient...

Detailed Description

PRIMARY OBJECTIVES: I. Conspicuity: Ia. To assess the conspicuity of idealized T1 and T2 imaging at detecting brain metastases at baseline. (Quantitative MRI) Ib. To assess the conspicuity (CNR) of ...

Eligibility Criteria

Inclusion

  • An adult patient with pathology-proven solid organ cancer
  • MRI of the brain with contrast, positive for at least one intra-axial metastatic lesion greater than 5 mm
  • Planned treatment with stereotactic radiation

Exclusion

  • Contraindication to MR imaging
  • Known allergy to gadolinium-based contrast agents
  • Renal failure as defined by a glomerular filtration rate (GFR) less than 30 or the use of hemodialysis
  • Pregnant
  • Patients less than 18 years of age will be excluded

Key Trial Info

Start Date :

March 30 2021

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

August 29 2023

Estimated Enrollment :

15 Patients enrolled

Trial Details

Trial ID

NCT04870645

Start Date

March 30 2021

End Date

August 29 2023

Last Update

November 6 2024

Active Locations (1)

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M D Anderson Cancer Center

Houston, Texas, United States, 77030