Status:

UNKNOWN

Cardiovascular Events Among Adults Patients With Relapsed or Refractory Aggressive B-Cell Lymphoma Treated With Standard of Care Chimeric Antigen Receptor T Cell Therapy

Lead Sponsor:

M.D. Anderson Cancer Center

Conditions:

Recurrent Aggressive B-Cell Non-Hodgkin Lymphoma

Recurrent Diffuse Large B-Cell Lymphoma

Eligibility:

All Genders

18+ years

Brief Summary

This study characterizes cardiac events following standard of care chimeric antigen receptor T cell therapy in patients with aggressive B-Cell Lymphoma that has come back (relapsed) or does not respon...

Detailed Description

PRIMARY OBJECTIVE: I. To characterize cardiac events following standard of Care (SOC) chimeric antigen receptor T (CAR-T) cell therapy in adult patients with relapsed/refractory aggressive B-cell lym...

Eligibility Criteria

Inclusion

  • Adults (\>= 18 years) with a diagnosis of aggressive B-cell lymphoma (such as transformed follicular lymphoma, diffuse large B-cell lymphoma, primary mediastinal B-cell lymphoma and high-grade B-cell lymphoma), who received standard of care (SOC) chimeric antigen receptor T (CAR-T) cell therapy at MD Anderson Cancer Center

Exclusion

  • None

Key Trial Info

Start Date :

April 2 2020

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

January 30 2025

Estimated Enrollment :

150 Patients enrolled

Trial Details

Trial ID

NCT04870853

Start Date

April 2 2020

End Date

January 30 2025

Last Update

November 14 2023

Active Locations (1)

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Page 1 of 1 (1 locations)

1

M D Anderson Cancer Center

Houston, Texas, United States, 77030