Status:

UNKNOWN

Effect of S-ketamine Anesthetic on Inflammatory Response in Septic Patients Undergoing Abdominal Surgery

Lead Sponsor:

Tianjin Nankai Hospital

Conditions:

Sepsis

Acute Lung Injury

Eligibility:

All Genders

18-85 years

Phase:

NA

Brief Summary

This study is a randomized, double-blinded, controlled design. In this study, low doses of S-ketamine were selected for surgury treatment in septic patients under general anesthesia , Meanwhile, activ...

Detailed Description

1. Title: Effect of S-ketamine Anesthetic on Inflammatory Response in Septic Patients Undergoing Abdominal Surgery 2. Research center: Single Center 3. The Design of the study: Randomized,double-blind...

Eligibility Criteria

Inclusion

  • Patients with sepsis requiring surgical treatment under general anesthesia should be transferred to ICU with endotracheal intubation for further treatment after surgery
  • 18≤ age ≤85, gender and nationality is not limited
  • Agree to participate in this study and sign the informed consent

Exclusion

  • Declined to participate in this study
  • Patients in pregnancy or with drug allergy in this study
  • Patient had chronic or acute respiratory ailments
  • long-term preoperative continuous ventilatory support or oxygen dependency
  • Patients are now being included in another study
  • In the opinion of the attending physician or researcher, there are other conditions that are not appropriate for the study

Key Trial Info

Start Date :

May 10 2021

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

October 30 2023

Estimated Enrollment :

50 Patients enrolled

Trial Details

Trial ID

NCT04873479

Start Date

May 10 2021

End Date

October 30 2023

Last Update

August 31 2021

Active Locations (1)

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Tianjin Nankai Hospital

Tianjin, Tianjin Municipality, China, 300000