Status:

RECRUITING

Taurine Effect on Glycemic, Lipidic and Inflammatory Profile in Individuals With Type 2 Diabetes

Lead Sponsor:

Hospital de Clinicas de Porto Alegre

Conditions:

Diabetes Mellitus, Type 2

Eligibility:

All Genders

30-80 years

Phase:

PHASE2

Brief Summary

Type 2 diabetes mellitus (DM2) is characterized by chronic hyperglycemia, which is a risk factor for comorbidities and death. Although conventional pharmacotherapy is effective, some individuals do no...

Detailed Description

A randomized, double-blind, placebo-controlled clinical trial will be conducted at Hospital de Clínicas de Porto Alegre (HCPA), Brazil. A total of 94 participants with DM2 will be recruited and random...

Eligibility Criteria

Inclusion

  • Inclusion criteria
  • Female and male individuals, with clinical diagnosis of DM2 for at least 6 months;
  • Age over 30 years;
  • BMC equal to or above 18.5 kg/m2, without weight change in the last 3 months;
  • HbA1c between 7.5% and 10.5%.
  • Exclusion criteria
  • Use of herbal supplements, antioxidants, and multivitamins in the last 3 months;
  • Pregnancy or lactation;
  • Chronic renal failure with glomerular filtration rate calculated by MDRD \< 30 mL/h;
  • Myocardial infarction in the last than 6 months
  • Current neoplasia;
  • Chronic use of glucocorticoids;
  • Bariatric surgery.

Exclusion

    Key Trial Info

    Start Date :

    June 12 2021

    Trial Type :

    INTERVENTIONAL

    Allocation :

    ESTIMATED

    End Date :

    December 1 2025

    Estimated Enrollment :

    94 Patients enrolled

    Trial Details

    Trial ID

    NCT04874012

    Start Date

    June 12 2021

    End Date

    December 1 2025

    Last Update

    September 19 2025

    Active Locations (1)

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    1

    Hospital de Clínicas

    Porto Alegre, Rio Grande do Sul, Brazil, 90630090