Status:
COMPLETED
Effect of Propfol Versus Sevoflurane on Auditory and Cognitive Function
Lead Sponsor:
Beni-Suef University
Conditions:
Cognitive Dysfunction
Auditory Dysfunction, Central
Eligibility:
All Genders
20-70 years
Phase:
PHASE4
Brief Summary
Perioperative hearing loss is a rarely reported phenomenon. However, it occurs more frequently than most anaesthesiologists suspect. Perioperative hearing impairment is often subclinical and may go un...
Detailed Description
Type and site of the study: This study will be carried out at Beni-Suef university hospital, after approval by the department of Anaesthesiology, the local ethics and research committee and other inv...
Eligibility Criteria
Inclusion
- ASA I-II patients who are candidate for elective extra cranial surgery.
- Male and female patients with age between 20-60 years
Exclusion
- Patients with a conductive or sensorineural hearing loss
- Patients with a history of ear infection
- Patients with a history of ear trauma
- Patients using ototoxic or neurotoxic drugs
- Patients with sternocleidomastoid muscle pathology (traumatic injury or weakness) that interfere with audiological assessment
- Patient subjected to gross hemodynamic or ventilatory fluctuations during the operation
- Patient who developed postoperative shock or major bleeding
- Patient with a history of neurodegenerative disease, concomitant medical or metabolic illness known to affect cognition
- Allergy to any drug used in the study.
- Pregnancy.
Key Trial Info
Start Date :
June 1 2021
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 1 2021
Estimated Enrollment :
80 Patients enrolled
Trial Details
Trial ID
NCT04874545
Start Date
June 1 2021
End Date
December 1 2021
Last Update
May 6 2022
Active Locations (1)
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1
Beni-Suef University
Banī Suwayf, Egypt, 62511