Status:

ACTIVE_NOT_RECRUITING

Tissue Engineering Approaches to Treat COPD

Lead Sponsor:

University Hospitals of North Midlands NHS Trust

Conditions:

Lung Cancer

Eligibility:

All Genders

18+ years

Brief Summary

The study is a pilot/laboratory study comparing lung tissue from control participants with tissue from COPD participants with a chronic bronchitis or emphysema phenotypes. Tissue will be characterised...

Detailed Description

Chronic obstructive pulmonary disease (COPD) is currently ranked as the third leading cause of death with an annual associated global healthcare cost of £1.3 trillion (1). It is the second most common...

Eligibility Criteria

Inclusion

  • Men or women aged over 18 years- .
  • Must be competent to give written informed consent.
  • Scheduled to undergo clinical indicated surgery to remove lung tissue.

Exclusion

  • Patient unable to give informed consent
  • Significant long term condition or lung pathology (infection, asthma, fibrotic lung diseases) other than that for which they have been referred for surgery.
  • Post Surgery
  • • Insufficient tissue removed to supply the laboratory study after consultation with the Consultant histopathologist.

Key Trial Info

Start Date :

August 31 2017

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

December 31 2025

Estimated Enrollment :

30 Patients enrolled

Trial Details

Trial ID

NCT04878445

Start Date

August 31 2017

End Date

December 31 2025

Last Update

February 4 2025

Active Locations (1)

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1

University Hospitals of North Midlands NHS Trust

Stoke-on-Trent, Staffordshire, United Kingdom, ST4 6QG