Status:

ACTIVE_NOT_RECRUITING

Role of CBD in Regulating Meal Time Anxiety in Anorexia Nervosa

Lead Sponsor:

University of California, San Diego

Conditions:

Anorexia Nervosa

Eligibility:

FEMALE

18-40 years

Phase:

EARLY_PHASE1

Brief Summary

No studies of cannabidiol (CBD) have focused on Anorexia Nervosa (AN). Dose, side effects, tolerability, acceptability of pure CBD in AN must be established. The current study is an important first st...

Eligibility Criteria

Inclusion

  • Must currently meet DSM-5 criteria for AN-R and AN Spectrum Disorders (i.e., Atypical AN) based on the Structured Clinical Interview for the DSM-5 (SCID-5-RV)
  • Have a duration of illness ≥ 6 months
  • Be medically stable as assessed by a comprehensive medical and behavioral evaluation conducted by a study physician

Exclusion

  • Psychotic illness/other mental illness requiring inpatient hospitalization
  • Current dependence on drugs or alcohol
  • Physical conditions (e.g., diabetes mellitus, pregnancy) known to influence eating or weight or liver disease which may affect pharmacokinetics of the study drug
  • Use of other psychoactive medications
  • Significant changes in medication in past month
  • Expression of acute suicidality
  • Previous hypersensitivity reaction to Epidiolex or any of its constituents

Key Trial Info

Start Date :

January 20 2022

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

June 1 2026

Estimated Enrollment :

40 Patients enrolled

Trial Details

Trial ID

NCT04878627

Start Date

January 20 2022

End Date

June 1 2026

Last Update

September 2 2025

Active Locations (1)

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Page 1 of 1 (1 locations)

1

University of California San Diego

San Diego, California, United States, 92121