Status:

COMPLETED

A Randomized Trial Evaluating EARLY Application of a Surfactant Dressing in Thermal Injury (EARLY)

Lead Sponsor:

University of Tennessee

Collaborating Sponsors:

Medline Industries

Conditions:

Burns

Partial-thickness Burn

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

The purpose of this study is to test the following hypotheses: 1. Early use of water-soluble surfactant dressing (WSD) on partial-thickness burn wounds will result in tissue salvage and reduce surgic...

Detailed Description

Surfactant-based wound dressings have been utilized in chronic, non-healing wounds and small burn wounds to soften and aid removal of wound debris. In vitro data suggest enhanced healing properties ar...

Eligibility Criteria

Inclusion

  • age ≥ 18 years old
  • admitted within 24 hours of injury
  • partial-thickness burn wounds on at least two non-contiguous areas of \< 10% TBSA each and not involving face, fingers, toes, and perineum
  • initial management assessed to require inpatient care

Exclusion

  • chemical, electrical, or inhalation injury
  • pregnant
  • incarcerated
  • TBSA ≥ 20%
  • wound expected to heal within 7 days
  • patient or authorized representative unable or unwilling to consent
  • unable to consent within 24 hours of injury

Key Trial Info

Start Date :

August 3 2021

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

October 24 2023

Estimated Enrollment :

27 Patients enrolled

Trial Details

Trial ID

NCT04880655

Start Date

August 3 2021

End Date

October 24 2023

Last Update

October 26 2023

Active Locations (1)

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Regional One Health

Memphis, Tennessee, United States, 38103