Status:
COMPLETED
The Effects Of Intravenous Ibuprofen on Pain, Oxidative Stress and Inflammation in Laparoscopic Hysterectomy Operations
Lead Sponsor:
Dr. Lutfi Kirdar Kartal Training and Research Hospital
Conditions:
Analgesia; Ibuprofen; Acetaminophen; Oxidative Stress
Eligibility:
FEMALE
30-65 years
Phase:
NA
Brief Summary
Objective: The aim of this study is to evaluate whether the exposure of oxidative stres in the peroperative period and the postoperative 24th hour can be decreased with the thiol-disulfide homeostasis...
Eligibility Criteria
Inclusion
- Elective Total Laparoscopic Hysterectomy, Aged between 30 and 65, Body Mass Index (BMI) below 35, ASA class I and II
Exclusion
- trauma patients to be operated in emergent conditions, ASA risk classification III-IV and more, have a postoperative intensive care indication, Active and clinical symptoms of anemia, Platelet level lower than 30000 / mm3, History of gastrointestinal bleeding in the last 6 months, History of bleeding diathesis or increased Patients at risk of intracerebral hemorrhage, Oliguric and / or need dialysis in the last 1 month before surgery, or have received dialysis, Patients who used a combination of Warfarin, Lithium, Angiotensin Converting Enzyme (ACE) inhibitor and Furosemide medication or who needed to use any analgesic, muscle relaxant or sedative medication within the last 24 hours.
- Patients who had a hypersensitivity reaction to any anesthetic or analgesic drug to be used in the study Patients did not want to participate in the study
Key Trial Info
Start Date :
January 2 2020
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 28 2020
Estimated Enrollment :
69 Patients enrolled
Trial Details
Trial ID
NCT04881474
Start Date
January 2 2020
End Date
December 28 2020
Last Update
May 11 2021
Active Locations (1)
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1
Kartal Dr. Lütfi Kırdar Training and Research Hospital
Istanbul, İ̇stanbul, Turkey (Türkiye), 34846