Status:

ACTIVE_NOT_RECRUITING

Treatment for Speech and Language in Primary Progressive Aphasia

Lead Sponsor:

University of Texas at Austin

Collaborating Sponsors:

National Institute on Deafness and Other Communication Disorders (NIDCD)

University of California, San Francisco

Conditions:

Primary Progressive Aphasia

Semantic Dementia

Eligibility:

All Genders

Phase:

NA

Brief Summary

Primary progressive aphasia (PPA) is a progressive neurological disorder that causes a gradual decline in communication ability as a result of selective neurodegeneration of speech and language networ...

Eligibility Criteria

Inclusion

  • Meets diagnostic criteria for Primary Progressive Aphasia (PPA; Gorno-Tempini et al., 2011)
  • Score of 15 or higher on the Mini-Mental State Examination

Exclusion

  • Other neurological or psychiatric diagnosis that may contribute to cognitive-linguistic deficits
  • Significant, uncorrected visual or hearing impairment that would interfere with participation
  • Score of less than 15 on the Mini-Mental State Examination
  • Prominent initial non-speech-language impairment (cognitive, behavioral, motoric)

Key Trial Info

Start Date :

July 1 2017

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

December 30 2025

Estimated Enrollment :

60 Patients enrolled

Trial Details

Trial ID

NCT04881617

Start Date

July 1 2017

End Date

December 30 2025

Last Update

November 13 2025

Active Locations (2)

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Page 1 of 1 (2 locations)

1

University of California San Francisco

San Francisco, California, United States, 94158

2

University of Texas

Austin, Texas, United States, 78712