Status:

ACTIVE_NOT_RECRUITING

COllaboration REsearch on Chronic Cough (COREC): a French Multicenter Database

Lead Sponsor:

University Hospital, Toulouse

Collaborating Sponsors:

MSD France

Conditions:

Refractory Chronic Cough

Eligibility:

All Genders

18+ years

Brief Summary

Chronic cough (TC), defined by a duration exceeding 8 weeks, is a particularly frequent symptom with a prevalence observed at 9.6% 1. Chronic cough is the cause of a major handicap for patients with a...

Detailed Description

Visit V1: Visit as part of the treatment After obtaining no objection, the patient will complete cough questionnaires Visit V2: Visit as part of the treatment Visit carried out at 3 months with evalu...

Eligibility Criteria

Inclusion

  • Age ≥18 years old
  • Consultation motivated by cough lasting for more than 8 weeks (duration corresponding to the definition of chronic cough)
  • Patient covered by a National Health Insurance

Exclusion

  • Active smoker or recent smoking cessation (within the past 6 months)
  • Intake of medications causing cough (the patient can be included 4 weeks after treatment discontinuation if cough persists)
  • Pregnant or breast-feeding women
  • Upper or lower respiratory tract infection within the past 4 weeks
  • Active lung disease (such as interstitial lung disease, lung cancer, abnormal dilation of the bronchi).
  • History of chronic bronchitis.
  • Current treatment with an angiotensin converting enzyme (ACE) inhibitor
  • History of cancer within the past 5 years or active cancer (excluding cutaneous squamous-cell carcinoma).
  • Person not fluent in French
  • Adult not able to express his/her consent verbally
  • Patient refusal

Key Trial Info

Start Date :

May 6 2021

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

June 1 2026

Estimated Enrollment :

576 Patients enrolled

Trial Details

Trial ID

NCT04882943

Start Date

May 6 2021

End Date

June 1 2026

Last Update

May 14 2021

Active Locations (1)

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Page 1 of 1 (1 locations)

1

UHToulouse

Toulouse, France, 31059