Status:

COMPLETED

SH-SS and GSH-GSSG Homeostasis in Post-stroke Patients

Lead Sponsor:

Abant Izzet Baysal University

Conditions:

Stroke

Eligibility:

All Genders

18+ years

Brief Summary

In patients undergoing physical therapy after stroke, extracellular thiol-disulfide balance and intracellular oxidized-reduced glutathione balance levels will be monitored. The main objectives of this...

Detailed Description

Stroke is among the most common causes of all deaths and Disability-Adjusted Life Years (DALYs) in the world. There is a close relationship between stroke pathophysiology and post-stroke clinic with o...

Eligibility Criteria

Inclusion

  • diagnosis of a first-ever stroke verified by computed tomography (CT) or magnetic resonance imaging (MRI) reports
  • admitted to the hospital for standard neurorehabilitation within 1 to 6 months of stroke onset
  • healthy individuals (for control group)

Exclusion

  • significant acute medical illness (e.g., autoimmune disease, infection, tumor, heart failure, renal or liver dysfunction)
  • significant acute neurological illness other than stroke (e.g., head trauma, brain abscess, brain tumor, migraine attack, seizure)
  • cannot adapt to work
  • previous history of neurorehabilitation therapy
  • taking the antioxidant supplements

Key Trial Info

Start Date :

July 1 2020

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

January 31 2021

Estimated Enrollment :

77 Patients enrolled

Trial Details

Trial ID

NCT04884555

Start Date

July 1 2020

End Date

January 31 2021

Last Update

May 13 2021

Active Locations (1)

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Bolu Abant Izzet Baysal University

Bolu, Turkey (Türkiye)