Status:

RECRUITING

Retrospective Observational Study on Prediction of Response to PD-1 Immunotherapy in Patients with NSCLC

Lead Sponsor:

University Hospital, Brest

Conditions:

Advanced Non Small Cell Lung Cancer

Eligibility:

All Genders

Brief Summary

Therapeutic antibodies that block the programmed death-ligand 1 (PD-L1)/programmed death-1 (PD-1) pathway have revolutionized immuno-oncology by inducing robust and durable responses in patients with ...

Eligibility Criteria

Inclusion

  • Adult patients
  • Advanced NSCLC with PD-L1 TPS of 50% or greater
  • Administration of first line pembrolizumab between January 2017 \& December 2019

Exclusion

  • Auto-immune disease
  • Prior exposure to immunotherapy
  • First dose pembrolizumab administered after December 2019

Key Trial Info

Start Date :

April 16 2021

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

May 16 2025

Estimated Enrollment :

50 Patients enrolled

Trial Details

Trial ID

NCT04886401

Start Date

April 16 2021

End Date

May 16 2025

Last Update

February 6 2025

Active Locations (1)

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1

CHRU de Brest

Brest, France, 29609