Status:

COMPLETED

Influence of Sex and Training on de Novo Muscle Protein Synthesis

Lead Sponsor:

University of Toronto

Collaborating Sponsors:

Natural Sciences and Engineering Research Council, Canada

Conditions:

Amino Acids

Dietary Protein

Eligibility:

All Genders

18-30 years

Brief Summary

Acute exercise increases the incorporation of dietary amino acids into de novo myofibrillar proteins after a single meal in controlled laboratory studies in males. It is unclear if this extends to fre...

Detailed Description

Exogenous (e.g. diet-derived) amino acids increase muscle protein synthesis and provide the building blocks for growth. While traditional infusion studies can measure the synthesis of total mixed musc...

Eligibility Criteria

Inclusion

  • Participants were included in the study after reporting not engaging in whole body RE or plyometrics in the past 3 months and had a BMI between 18.5-27.5 kg/m2.
  • Females were included if they had a regular menstrual cycle with the last 3 months and

Exclusion

  • Participants were excluded if they: i) consumed tobacco and/or illicit anabolic drug use (e.g. testosterone, growth hormones); ii) were a vegan or had a nut allergy and; iii) participated in a study within the past year involving stable isotopes.
  • Females were excluded if they used oral contraceptives and/or discontinued their use within the last 3 months.

Key Trial Info

Start Date :

January 1 2019

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

September 1 2019

Estimated Enrollment :

20 Patients enrolled

Trial Details

Trial ID

NCT04887883

Start Date

January 1 2019

End Date

September 1 2019

Last Update

May 14 2021

Active Locations (1)

Enter a location and click search to find clinical trials sorted by distance.

Page 1 of 1 (1 locations)

1

Goldring Centre for High Performance Sport

Toronto, Ontario, Canada, M9L 1C5