Status:

UNKNOWN

Evaluation the Effectiveness of Ru-Yi-Jin-Huang Powder for the Radiation-induced Dermatitis.

Lead Sponsor:

Chang Gung Memorial Hospital

Conditions:

Radiation Dermatitis

Eligibility:

All Genders

18-80 years

Phase:

PHASE2

Brief Summary

Radiation-induced dermatitis is the most common complication of radiotherapy for cancer treatment. However, there is no satisfactory management to deal with the problem. Ru-Yi-Jin-Huang Powder is one ...

Detailed Description

The common management of head and neck cancer are concurrent chemoradiotherapy (CCRT) after surgical section. Radiation-induced dermatitis is the most common complication of radiotherapy for cancer, a...

Eligibility Criteria

Inclusion

  • stage 3 or 4 of head and neck cancer or nasopharyngeal cancer with pathological confirmed malignancy undergoing concurrent chemoradiotherapy more than 20 times or radiation dermatitis \> CTCAE grade 2.
  • more than 18 years old.
  • VAS score \> 6 with poor response to narcotics.
  • estimated survival time of \> 6 months.
  • be suitable for TCM topical treatment after evaluation by TCM physicians.
  • willingness to joint this trial and sign consent form of study.

Exclusion

  • non-head and neck cancer or have not receive CCRT.
  • not be suitable for Ru-Yi-Jin-Huang topical treatment after TCM physicians evaluation.
  • history of allergy to TCM topical use.
  • poor conscious to answer questionnaires.
  • pregnancy.
  • KPS \< 30.

Key Trial Info

Start Date :

May 8 2021

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

July 30 2022

Estimated Enrollment :

30 Patients enrolled

Trial Details

Trial ID

NCT04888234

Start Date

May 8 2021

End Date

July 30 2022

Last Update

May 17 2021

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