Status:
RECRUITING
68Ga-HA-DOTATATE Imaging of Suspected Somatostatin Receptor Positive Tumors
Lead Sponsor:
University of Alberta
Conditions:
Neuroendocrine Tumors
Eligibility:
All Genders
Phase:
PHASE2
Brief Summary
Somatostatin receptor (SSR) imaging is a critical component of clinical care for many patients being investigated for or with confirmed SSR positive tumors. In the past, 111In-octreotide imaging has b...
Detailed Description
A single centre non-randomized, non-blinded phase II prospective cohort study evaluating the safety and efficacy of 68Ga-HA-DOTATATE PET/CT imaging in patients with known or suspected somatostatin rec...
Eligibility Criteria
Inclusion
- Patients with known or clinically suspected somatostatin receptor positive tumors including but not limited to: gastrointestinal neuroendocrine tumors, pancreatic neuroendocrine tumors, pulmonary neuroendocrine tumors, neuroendocrine tumors - primary unknown, pheochromocytoma, paraganglioma, medullary thyroid cancer, medulloblastoma, meningioma
- A standard clinical CT or MRI is obtained within 6 months of enrollment
- Ability to provide written informed consent prior to participation in the study (participant or if required a legal medical decision maker)
Exclusion
- Weight \> 225 kg (weight limit of the PET/CT scanner)
- Inability to scan (ie. extreme claustrophobia) or inability to lie still for imaging
- Any additional medical condition, serious inter-current illness, or other extenuating circumstance that, in the opinion of the investigator or attending department physician, may significantly interfere with study performance or interpretation
- Previous allergic reaction to DOTATATE or somatostatin analogues
- Lack of intravenous access
Key Trial Info
Start Date :
February 15 2022
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
August 31 2028
Estimated Enrollment :
600 Patients enrolled
Trial Details
Trial ID
NCT04888481
Start Date
February 15 2022
End Date
August 31 2028
Last Update
May 7 2025
Active Locations (1)
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1
University of Alberta
Edmonton, Alberta, Canada, T6G 2B7