Status:

ACTIVE_NOT_RECRUITING

A Prospective Cohort for ex Vivo Cure Studies With Chronic HIV Infected Patients in the Netherlands

Lead Sponsor:

Erasmus Medical Center

Conditions:

HIV Infections

HIV-1-infection

Eligibility:

All Genders

18+ years

Brief Summary

A prospective non-interventional cohort study at Erasmus MC of adult chronic HIV infected patients of ≥18 years of age who initiate antiretroviral therapy in routine care.

Detailed Description

HIV cannot be cured with the current treatment armamentarium. A reservoir of latently HIV infected long lived CD4+T-cells is present in patients with HIV that are not affected by antiretroviral therap...

Eligibility Criteria

Inclusion

  • Age \>18 years.
  • Confirmed HIV-1 or HIV-2 infection
  • Judged willing to initiate and adhere to cART by the HIV physician.

Exclusion

  • Inability to place venous catheters to draw blood.
  • Major comorbidities:
  • Severe symptomatic anemia or recent symptomatic cardiovascular event (un-stable angina pectoris, decompensated heart failure, myocardial infarction).
  • The inability to participate due to any other relevant social, environmental,psychological, factors or according to the HIV treating physician's judgement.

Key Trial Info

Start Date :

May 26 2021

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

January 1 2034

Estimated Enrollment :

35 Patients enrolled

Trial Details

Trial ID

NCT04888754

Start Date

May 26 2021

End Date

January 1 2034

Last Update

February 13 2024

Active Locations (1)

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Erasmus MC

Rotterdam, Netherlands, 3015 CN