Status:
RECRUITING
Coronary Artery Calcification in Type 2 Diabetes Mellitus (USCAC Study)
Lead Sponsor:
University of South China
Conditions:
Type 2 Diabetes
Vascular Calcification
Eligibility:
All Genders
18+ years
Brief Summary
Coronary artery calcification (CAC) is a common complication of type 2 diabetes mellitus(T2DM), which can significantly increase all-cause mortality and the incidence of serious cardiovascular events,...
Detailed Description
The prospective cohort study of type 2 diabetes mellitus(T2DM) with coronary artery calcification (CAC) is a multi-center, observational clinical study. The study included a baseline survey and 8-year...
Eligibility Criteria
Inclusion
- Age ≥ 18 years old
- Type 2 diabetes is diagnosed according to WHO diagnostic criteria
- Low dose prospectively triggered sequential dual-source CT coronary angiography can be performed at baseline investigation
- Those subjects are able to understand the purpose and procedure of this study and sign the informed consent voluntarily
Exclusion
- Those have received coronary artery stenting or coronary artery bypass grafting
- Those with severe lung (respiratory failure), liver (ALT or AST 3 times normal value or bilirubin increase), renal dysfunction\[GFR \< 45ml/(min.1.73m2) or dialysis patients
- Malignant tumor
- Mental illness or mental retardation
- Pregnant or lactating women or those with fertility planning
- Concomitant diseases (hyperparathyroidism, sarcoidosis, amyloidosis) affecting calcium balance and soft tissue calcification
- Contraindications of contrast agents
- Based on the judgment of the researcher, the compliance is poor and the study could not be completed according to the requirements
Key Trial Info
Start Date :
June 1 2021
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 31 2030
Estimated Enrollment :
1400 Patients enrolled
Trial Details
Trial ID
NCT04889053
Start Date
June 1 2021
End Date
December 31 2030
Last Update
September 29 2021
Active Locations (1)
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1
The First Affiliated Hospital of University of South China
Hengyang, China