Status:

RECRUITING

Observational Study in Localized Osteosarcoma

Lead Sponsor:

Italian Sarcoma Group

Collaborating Sponsors:

Associazione Italiana Ematologia Oncologia Pediatrica

Conditions:

Localized Osteosarcoma

Eligibility:

All Genders

Up to 40 years

Brief Summary

Observational prospective trial aimed to collect the collect demographic, clinical, surgical, pathological and molecular characteristics and treatment from patients affected by localized OsteoSarcoma ...

Detailed Description

Osteosarcoma is the most frequent primary malignant bone tumor in children and adolescents and is considered a rare disease. The overall incidence of OS is 0.2-3 / 100,000 inhabitants per year with a...

Eligibility Criteria

Inclusion

  • Diagnosis of high grade OS of the extremities
  • Age at diagnosis ≤ 40 years at the time of diagnosis
  • Localized disease (skip metastases are allowed)
  • Adequate organ function according the AIEOP/ISG OS 2021 recommendation
  • Patients or parents oe guardians of minors who have given their written informed consent to participate in the study

Exclusion

  • Presence of metastases
  • Diagnosis of periosteal OS, of parosteal OS or secondary OS
  • Any medical condition which can not allowed the use of the treatments recommended by AIEOP/ISG OS 2021

Key Trial Info

Start Date :

July 30 2021

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

December 30 2026

Estimated Enrollment :

120 Patients enrolled

Trial Details

Trial ID

NCT04890067

Start Date

July 30 2021

End Date

December 30 2026

Last Update

March 10 2025

Active Locations (16)

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Page 1 of 4 (16 locations)

1

Centro di Riferimento Oncologico - Unit of Medical Oncology

Aviano, Pordenone, Italy, 33081

2

Sandra Aliberti

Candiolo, Torino, Italy, 10060

3

IRCCS materno infantile Burlo Garofolo

Trieste, T, Italy, 34137

4

Azienda Ospedaliero Universitaria Consorziale Policlinico - Bari

Bari, Italy, 70124