Status:
UNKNOWN
Gut Microbiota in Patients With Moyamoya Disease
Lead Sponsor:
Beijing Tiantan Hospital
Conditions:
Moyamoya Disease
Gut Microbiota
Eligibility:
All Genders
2-60 years
Brief Summary
This study is to find out the association between gut microbiota and moyamoya disease.
Detailed Description
Moyamoya disease (MMD) is a rare cerebrovascular disorder, it is a major cause of stroke in children and young adults in Japan, Korea, and China, but its pathogenesis is not yet clear. Dysbiosis of gu...
Eligibility Criteria
Inclusion
- Diagnosis of MMD by DSA according to the Japanese guidelines published in 2012,
- Stenosis or occlusion of the terminal internal carotid and the proximal middle and anterior cerebral arteries and unilateral or bilateral involvement
- Age: 2-60 years old.
Exclusion
- Moyamoya syndrome,
- Pregnancy,
- Evidence of gastrointestinal infection/ inflammation/ obstruction
- History of partial or total resection of small or large bowel, as well as gut reanastomosis,
- Use of antibiotics within 2 weeks prior to symptoms onset,
- Gastrointestinal malignancy
- Any hospitalization within 3 months before recruitment
Key Trial Info
Start Date :
May 1 2021
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 31 2021
Estimated Enrollment :
120 Patients enrolled
Trial Details
Trial ID
NCT04890782
Start Date
May 1 2021
End Date
December 31 2021
Last Update
May 18 2021
Active Locations (1)
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1
Beijing Tiantan Hospital Capital Medical University
Beijing, Beijing Municipality, China, 100000