Status:

COMPLETED

Effect of Ondansetron on Spinal-induced Hypotension for Percutaneous Nephrolithotomy

Lead Sponsor:

Mansoura University

Conditions:

Percutaneous Nephrolithotomy

Eligibility:

All Genders

25-60 years

Phase:

EARLY_PHASE1

Brief Summary

Percutaneous nephrolithotomy (PCNL) is the surgical standard for treating large or complex renal stones. The stones are removed by passing a small telescope through the side of the patient directly in...

Detailed Description

This study aims to assess the effect of Ondansetron on spinal induced hypotension when bupivacaine and dexmedetomidine are used intrathecally during spinal anesthesia for percutaneous nephrolithotomy....

Eligibility Criteria

Inclusion

  • Patients scheduled for PCNL surgery.
  • ASA classification I or II

Exclusion

  • Patient refusal
  • Contraindication to spinal anesthesia.
  • Known allergy to Ondansetron.
  • Uncontrolled hypertensive patient.
  • Ischemic heart diseases.
  • Moderate to severe stenotic valve lesion.
  • Atrial fibrillation.

Key Trial Info

Start Date :

April 1 2021

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

September 1 2022

Estimated Enrollment :

90 Patients enrolled

Trial Details

Trial ID

NCT04891484

Start Date

April 1 2021

End Date

September 1 2022

Last Update

September 26 2022

Active Locations (1)

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Page 1 of 1 (1 locations)

1

Urology and nephrology center

Al Mansurah, Dakahlia Governorate, Egypt, 050