Status:
COMPLETED
Prophylaxis for COVID-19: Ivermectin in Close Contacts of COVID-19 Cases (IVERNEX-TUC)
Lead Sponsor:
Ministry of Public Health, Argentina
Conditions:
Covid19
Eligibility:
All Genders
18-60 years
Phase:
PHASE2
PHASE3
Brief Summary
Randomized controlled clinical trial on using oral ivermectin in COVID-19 prophylaxis supplying the drug to close contacts of confirmed cases.
Detailed Description
This is a randomized, double-blind, and controlled clinical trial that aims to evaluate the use of oral ivermectin in COVID-19 prophylaxis. The study has two arms in a relationship of 2:1: Experimenta...
Eligibility Criteria
Inclusion
- Over 18 years either sex
- Women of childbearing age with a negative pregnancy test
- In close contact group or epidemiological nexus of a positive COVID-19 case
- Able to understand and grant informed consent
- Real-time - polymerase chain reaction test with a negative result
Exclusion
- Known hypersensitivity or allergy to any component of the drug under evaluation
- Age under 18 years
- Use of immunosuppressants (including systemic corticosteroids) in the last 30 days
- Pregnant or lactating
- Patients with other acute infectious diseases
- Patients with autoimmune disease and/or chronic decompensated diseases
- Who have received a vaccine for COVID-19 (1/2 dose) or that have taken ivermectin (prior to 30 days of the study) or who are participating in another COVID-19 prophylaxis study
Key Trial Info
Start Date :
June 1 2021
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
October 1 2021
Estimated Enrollment :
172 Patients enrolled
Trial Details
Trial ID
NCT04894721
Start Date
June 1 2021
End Date
October 1 2021
Last Update
December 7 2021
Active Locations (1)
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1
SI.PRO.SA, Ministerio de Salud Pública
San Miguel de Tucumán, Argentina, 4000