Status:

COMPLETED

Upper Extremity Exercise Capacity, Muscle Oxygenation, Balance in Patients With Primary Ciliary Dyskinesia

Lead Sponsor:

Gazi University

Conditions:

Primary Ciliary Dyskinesia

Eligibility:

All Genders

6-18 years

Brief Summary

The main aim of the study is to evaluate upper extremity exercise capacity and muscle oxygenation in patients with primary ciliary dyskinesia. The secondary aim of the study is to evaluate respiratory...

Detailed Description

Primary ciliary dyskinesia (PCD) is a genetic, heterogeneous disease caused by cilia absence or dysfunction. Impaired function of motile cilia leads to impaired mucociliary clearance, recurrent chest ...

Eligibility Criteria

Inclusion

  • Patients;
  • 6-18 years old
  • Diagnosed with primary ciliary dyskinesia
  • Stability of clinical condition
  • Healthy controls;
  • 6-18 years old

Exclusion

  • Patients;
  • Diagnosed neurological, cognitive problem that can affect evaluations,
  • Acute pneumonia or any infection
  • History of exacerbation in the last 1 month
  • More than 10% change in FEV1 in the last 6 months
  • History of coronavirus disease (COVID-19)
  • History of smoking
  • Diagnosed vision, hearing, vestibular, or neurological problems that can affect balance
  • Diagnosed orthopedic problems affecting mobility or a history of musculoskeletal surgery
  • Healthy controls;
  • Diagnosed neurological, cognitive problem that can affect evaluations
  • Diagnosed vision, hearing, vestibular, or neurological problems that can affect balance
  • History of coronavirus disease (COVID-19)
  • History of smoking
  • Trouble understanding and following the exercise test instruction

Key Trial Info

Start Date :

June 1 2021

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

May 15 2022

Estimated Enrollment :

54 Patients enrolled

Trial Details

Trial ID

NCT04895150

Start Date

June 1 2021

End Date

May 15 2022

Last Update

May 19 2022

Active Locations (2)

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Page 1 of 1 (2 locations)

1

Gazi University, Faculty of Health Science

Ankara, Turkey (Türkiye)

2

Gazi University

Ankara, Turkey (Türkiye)