Status:

TERMINATED

Swiss Study of the Impact of Mayzent on SPMS Patients in a Long-term Non-interventional Study

Lead Sponsor:

Novartis Pharmaceuticals

Conditions:

Secondary Progressive Multiple Sclerosis With Inflammatory Disease Activity

Eligibility:

All Genders

18+ years

Brief Summary

This study is a national, prospective, multicenter, non-interventional (observational) study with the aim to describe the impact of Siponimod treatment in a real-world SPMS population in Switzerland w...

Detailed Description

Primary data will be collected during an observational period of three years of Siponimod treatment. Additionally, medical history of participants will be collected including EDSS, MRI outcomes, relap...

Eligibility Criteria

Inclusion

  • Signed informed consent
  • Adult patients with a documented diagnosis of SPMS with inflammatory disease activity who are going to be treated with Siponimod under routine medical care and in accordance with the Swiss label
  • Patient willing and able to complete the questionnaires

Exclusion

  • Patients treated outside of the approved Swiss label for Siponimod
  • Prior treatment or already ongoing treatment with Siponimod
  • Use of investigational drugs during the study, OR within 3 months before enrollment, OR within 5 half-lives of investigational drug before enrollment, OR until the expected pharmacodynamic effect has returned to baseline, whichever is longer
  • Subjects who are not able to provide consent due to incapable judgement

Key Trial Info

Start Date :

November 19 2021

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

December 20 2022

Estimated Enrollment :

8 Patients enrolled

Trial Details

Trial ID

NCT04895202

Start Date

November 19 2021

End Date

December 20 2022

Last Update

August 29 2023

Active Locations (6)

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Page 1 of 2 (6 locations)

1

Novartis Investigative Site

Zug, Canton of Zug, Switzerland, 6300

2

Novartis Investigative Site

Zurich, Canton of Zurich, Switzerland, 8006

3

Novartis Investigative Site

Basel, Switzerland, 4031

4

Novartis Investigative Site

Bern, Switzerland, 3010