Status:

UNKNOWN

Progesterone Supplementation on Women Having Low Progesterone Levels on Transfer Day

Lead Sponsor:

Tu Du Hospital

Conditions:

Assisted Reproductive Technology

Eligibility:

FEMALE

18-45 years

Phase:

PHASE3

Brief Summary

The main objective of this study is to compare clinical pregnancy rates between two groups of women who have progesterone levels below 10 ng/mL on the day of frozen embryo transfer: group 1 (vaginal m...

Detailed Description

Trial Design: Single center, longitudinal, randomized, interventional, controlled, pharmacological study, enrolling women attending clinical Centers of medically assisted reproduction (ART). The stu...

Eligibility Criteria

Inclusion

  • Patients undergone ART with frozen embryo transfer, blastocyst or cleavaged stage embryo transfer, from 18-45 years of age
  • Normal BMI
  • HRT for Endometrial preparation in FET cycles

Exclusion

  • Oocyte donor cycles
  • Surrogacy
  • IVM
  • PGT
  • Abnormal Uterine (firbroids 0 -\> 3 according to FIGO classification, polyp, adenomyosis, congenital malformation)
  • Uterus fibroids type 4,5 (Figo classification) \> 4cm
  • History of recurrent implantation failure
  • Endometrial thickness \<7mm on the day of ET
  • Cesarean scar defect (isthmocele)

Key Trial Info

Start Date :

May 20 2021

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

June 20 2024

Estimated Enrollment :

824 Patients enrolled

Trial Details

Trial ID

NCT04897269

Start Date

May 20 2021

End Date

June 20 2024

Last Update

December 11 2023

Active Locations (1)

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1

Department of Infertility of Tu Du hospital

Ho Chi Minh City, Vietnam, 70000