Status:

COMPLETED

A Study to Evaluate the Effects of Sharpened Romberg Testing (SRT) in Healthy Subjects

Lead Sponsor:

Mayo Clinic

Conditions:

Hypocapnia

Balance; Distorted

Eligibility:

All Genders

21-55 years

Phase:

NA

Brief Summary

This research study is being done to evaluate the effectiveness of using the sharpened Romberg test to screen for impaired postural control in patients with impaired or altered breathing patterns.

Detailed Description

The effects of hypocapnia on the postural system have not previously been adequately investigated. The specific aim of this study is to evaluate the effects of hypocapnia on postural standing balance ...

Eligibility Criteria

Inclusion

  • \- Research subject conditions that may result in alterations of ventilatory control (capnic status) and balance will be specifically reviewed as criteria for participation.

Exclusion

  • Current pregnancy in women, alcohol use within the past 3 days prior to the experiment, history of balance problems (e.g., vertigo, neuropathy, central or peripheral vestibular disorders), and musculoskeletal disorders affecting the ability to perform a SRT in participants.
  • Patients currently taking carbonic anhydrase inhibitors, opioids, benzodiazepines, hypnotics, first-generation H1 antihistamines, amphetamines, and first-generation antipsychotics.
  • Patients with a history of insomnia, sleep apnea, circadian rhythm disturbances, narcolepsy, movement disorders, chronic low blood pressure, fainting spells, multiple concussions, seizure disorders, migraines, severe headaches and panic attacks.
  • If the patient took medications known to cause prolonged QTc interval and other cardiac arrhythmias, the researchers will exclude the patient from the study.

Key Trial Info

Start Date :

May 17 2021

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

January 1 2023

Estimated Enrollment :

20 Patients enrolled

Trial Details

Trial ID

NCT04897360

Start Date

May 17 2021

End Date

January 1 2023

Last Update

January 17 2023

Active Locations (1)

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Mayo Clinic in Arizona

Scottsdale, Arizona, United States, 85259