Status:

RECRUITING

Effect of Blenderized Enteral Tube Feeds on Pediatric Upper Gastrointestinal Tract Physiology

Lead Sponsor:

Boston Children's Hospital

Conditions:

Enteral Feeding Intolerance

Eligibility:

All Genders

1+ years

Phase:

NA

Brief Summary

Blenderized diets consist of a wide range of table foods such as fruits, vegetables, meat and legumes, pureed in a blender and administered via gastrostomy tube. In a recent study, the investigators r...

Detailed Description

The investigators hypothesize that rates of gastroesophageal reflux will be lower in blenderized diets compared to formula. The investigators will determine if reflux burden as measured by multichanne...

Eligibility Criteria

Inclusion

  • Age 1-21 years
  • G-tube
  • Able to tolerate bolus gastric feeds over 30 minutes
  • Use of conventional enteral formula
  • Undergoing impedance study for clinical purposes

Exclusion

  • History of allergy or intolerance to any component of the test diets
  • History of Nissen fundoplication (participants with suspected or documented unwrapped fundoplication will be eligible for participation)
  • Current use of non-invasive pressure support (continuous or bi-level positive airway pressure)

Key Trial Info

Start Date :

August 1 2021

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

December 1 2025

Estimated Enrollment :

45 Patients enrolled

Trial Details

Trial ID

NCT04900597

Start Date

August 1 2021

End Date

December 1 2025

Last Update

February 12 2025

Active Locations (1)

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Page 1 of 1 (1 locations)

1

Boston Children's Hospital

Boston, Massachusetts, United States, 02115