Status:
COMPLETED
Impact of Yogurt on Gastrointestinal Health, Regularity, and Thoughts
Lead Sponsor:
University of Illinois at Urbana-Champaign
Collaborating Sponsors:
National Honey Board
Conditions:
Gastrointestinal Dysfunction
Physiological Stress
Eligibility:
All Genders
22-64 years
Phase:
NA
Brief Summary
This study aims to test the central hypothesis that adding to the diet daily yogurt provides beneficial effects on digestive health and subjective mood in healthy adults.
Detailed Description
This clinical trial will include a 4-week lead-in period and a 2-week treatment period. The lead-in period will be devoid of all supplemental and dietary probiotics, fermented dairy products, and ferm...
Eligibility Criteria
Inclusion
- Males and females
- Between the ages of 22-64 years at the time of consent
- Body mass index of 18.5 to 29.9 kg/m\^2.
- Normal or corrected-to-normal vision based on the minimal 20/20 standard in order to complete the cognitive task (below 20/20 vision).
- Ability to drop off fecal sample within 30 minutes of defecation
- Have between 3-6 bowel movements per week
- Have completed the NECTAR Study (NCT04187950)
Exclusion
- Current pregnancy, lactation, or post-menopausal
- Tobacco use
- Honey allergy or intolerance
- Dairy allergy, lactose intolerance
- Food dye allergy/intolerance
- Prior physician diagnosed gastrointestinal disease (chronic constipation, diarrhea, Crohn's disease, celiac disease, ulcerative colitis, irritable bowel syndrome, diverticulosis, stomach or duodenal ulcers, hepatitis, or gastroesophageal reflux disease (GERD))
- Current use or use of antibiotics in the past 3 months
- Current use of any of the following types of medications: laxatives, anti-diarrhea medications, narcotics, enemas, antispasmodics, anticonvulsants, prescription proton pump inhibitors, prokinetic agents, histamine-2 Rc antagonists (prescription GERD medication)
- Body mass index \> 29.9 kg/m\^2
- Prior malabsorptive bariatric surgery (i.e. gastric bypass, sleeve gastrectomy)
- Restrictive bariatric surgery (i.e. adjustable gastric band) within the past 5 years
- Concurrent enrollment in another dietary, exercise, or medication study (except for the NECTAR Study (NCT04187950))
Key Trial Info
Start Date :
September 20 2021
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
November 23 2022
Estimated Enrollment :
66 Patients enrolled
Trial Details
Trial ID
NCT04901390
Start Date
September 20 2021
End Date
November 23 2022
Last Update
July 21 2023
Active Locations (1)
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1
University of Illinois at Urbana-Champaign
Urbana, Illinois, United States, 61801