Status:
COMPLETED
Acute Effects of High Intensity Training on Pain Processing and Inflammation in Chronic Low Back Pain.
Lead Sponsor:
Hasselt University
Collaborating Sponsors:
Jessa Hospital
Conditions:
Low Back Pain
Inflammation
Eligibility:
All Genders
18-65 years
Phase:
NA
Brief Summary
A multitude of exercise therapy modalities are effective in improving daily physical function and relieving pain in various forms of chronic musculoskeletal pain (CMP) such as chronic neck pain, osteo...
Detailed Description
Chronic musculoskeletal pain (CMP) currently affects up to 20% of all people or about 1.5 billion persons worldwide, and these numbers continue to increase steadily. CMP can have a significant impact ...
Eligibility Criteria
Inclusion
- Inclusion criteria for group 1 (persons with chronic low back pain)
- Primary complaint: non-specific chronic low back pain.
- Low back pain is defined as pain in the area between the lower ribs and the upper buttock crease, with or without radiation in the leg
- Chronic: current episode \> 12 weeks, mean pain intensity between 3-8/10
- Non-specific: the main pain cannot be traced back to a known pathology
- Age: 18-65 years
- Acute pain intensity at the time of testing between 3-8/10 (i.e. a pain intensity within this range is necessary to obtain a correct estimate of the pain response)
- Understanding of the Dutch language (written and spoken)
- Inclusion criteria for group 2 (healthy persons)
- No acute or chronic musculoskeletal complaints (i.e. VAS\> 2/10 in the last 24 hours)
- Age: 18-65 years
- Understanding of the Dutch language (written and spoken)
- Exclusion criteria for both group 1 and 2
- Invasive spinal surgery within the last 18 months (arthrodesis will always be excluded, microsurgery is allowed)
- Radiculopathy (uni- or bilateral) of the lower extremities
- Comorbidities: paresis and sensory disturbances with a neurological cause in the lower extremities, diabetes mellitus, rheumatoid arthritis, autoimmune disorders etc.
- Pregnancy
- Ongoing compensation complaints and/or incapacity for work \> 6 months
- Previous active rehabilitation (i.e. exercise therapy) for low back pain in the last 6 months.
Exclusion
Key Trial Info
Start Date :
February 24 2021
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 31 2022
Estimated Enrollment :
40 Patients enrolled
Trial Details
Trial ID
NCT04902196
Start Date
February 24 2021
End Date
December 31 2022
Last Update
April 5 2023
Active Locations (1)
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1
Jessa Ziekenhuis
Hasselt, Belgium, 3500