Status:
ACTIVE_NOT_RECRUITING
Dairy and Inflammation Study
Lead Sponsor:
York University
Collaborating Sponsors:
Dairy Farmers of Canada
Conditions:
Inflammation
Overweight and Obesity
Eligibility:
All Genders
18-70 years
Phase:
NA
Brief Summary
The purpose of this study is to determine whether 6-weeks of increased dairy consumption can reduce inflammation and other markers of chronic disease while fasted or following a high-fat meal.
Detailed Description
Following the acquisition of informed consent, eligibility to participate in the study will be determined using questionnaires, and certain parameters determined from a finger-prick blood sample. Elig...
Eligibility Criteria
Inclusion
- Body mass index (BMI) ≥ 25 kg/m2
- ≤ 2 structured exercise sessions/week
- Habitual low dairy consumption (≤ 1 serving/day)
- Having at least two other metabolic risk factors based on clinical guidelines:
- Elevated blood pressure (≥130/≥85 mm Hg)
- Impaired fasting glucose (≥5.6 mmol/L) measured using a finger prick sample
- Impaired fasting triglycerides (≥1.7 mmol/L) or high-density lipoprotein (\<1.03 mmol/L for males, \<1.3 mmol/L for females) measured using a finger prick blood sample.
- Increased waist circumference (≥102 cm for males and ≥88 cm for females).
- Borderline high fasting low-density lipoprotein (≥3.5 mmol/L) or total cholesterol (≥5.2 mmol/L).
Exclusion
- Allergy to dairy foods, diagnosed lactose intolerance or an aversion to foods provided during the study
- Previous history of diabetes and/or related cardiovascular disease
- The use of multiple medications for managing lipids, glucose and/or blood pressure
Key Trial Info
Start Date :
May 1 2022
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 30 2024
Estimated Enrollment :
32 Patients enrolled
Trial Details
Trial ID
NCT04902417
Start Date
May 1 2022
End Date
December 30 2024
Last Update
June 21 2024
Active Locations (1)
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1
York University
Toronto, Ontario, Canada, M3J 1P3