Status:

UNKNOWN

Gonadal Changes In Congenital Adrenal Hyperplasia Patients

Lead Sponsor:

Ain Shams University

Conditions:

Congenital Adrenal Hyperplasia

Eligibility:

All Genders

5-16 years

Brief Summary

To detect the prevalence of gonadal changes by US among the patients with CAH. * assess the patients' radiological findings in relation to their hormonal profile. * early management and prevention of...

Detailed Description

Several factors contribute to the impaired fertility in CAH patients, such as androgen excess, adrenal progesterone hypersecretion and adrenal rest tumours (ARTs). ARTs are derived from ectopic adrena...

Eligibility Criteria

Inclusion

  • All patients diagnosed with CAH between five and 16 years of age will be asked to participate in this cross sectional study.
  • Compliant patients with regular follow up.

Exclusion

  • Presence of other endocrinal diseases or chronic conditions.
  • Female patients with ovulatory dysfunction from other causes including thyroid dysfunction and hyperprolactinemia.
  • Male patients with other diseases causing impairment of gonadal capacity.

Key Trial Info

Start Date :

October 1 2021

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

November 1 2022

Estimated Enrollment :

50 Patients enrolled

Trial Details

Trial ID

NCT04903587

Start Date

October 1 2021

End Date

November 1 2022

Last Update

December 30 2021

Active Locations (1)

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1

Ain Shams University

Cairo, Egypt