Status:

COMPLETED

Effects of Low/No Calorie Sweeteners on Glucose Tolerance

Lead Sponsor:

Acibadem University

Conditions:

Healthy Population

Glucose Tolerance

Eligibility:

FEMALE

19-45 years

Phase:

NA

Brief Summary

This study aims to determine the effects of chronic exposure to some low/no calorie sweeteners (LNCS) on glucose tolerance and glucagon like peptide 1 (GLP-1) release in healthy individuals. LNCS exam...

Detailed Description

Excessive sugar consumption has been related to chronic metabolic problems, including obesity, type 2 diabetes, neuroinflammatory diseases, etc. Therefore, it is recommended to decrease added sugar in...

Eligibility Criteria

Inclusion

  • Healthy,
  • Normoglycemic,
  • Female,
  • 19-45 years old,
  • Weight-stable past 3 months

Exclusion

  • Insulin resistance,
  • Type 2 diabetes mellitus,
  • Presence of acute/chronic infection,
  • Use of medication that may affect glucose metabolism (thiazide diuretics, glucocorticoids, estrogen or beta blockers)
  • Chronic alcohol intake,
  • Regular consumption of diet soda (more than one can of soda per week)

Key Trial Info

Start Date :

April 2 2019

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

July 2 2019

Estimated Enrollment :

42 Patients enrolled

Trial Details

Trial ID

NCT04904133

Start Date

April 2 2019

End Date

July 2 2019

Last Update

May 27 2021

Active Locations (1)

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Acıbadem Dr. Şinasi Can (Kadıköy) Hospital

Istanbul, Anadolu, Turkey (Türkiye), 34718